Table 2 Main laboratory parameters before and after the extracorporeal treatments.
From: Extracorporeal cell therapy of septic shock patients with donor granulocytes: a pilot study
Parameter | Unit | Before extracorporeal treatment n= 20 | After 6 h extracorporeal treatment n= 20 | P-value |
|---|---|---|---|---|
Inflammation | ||||
Leukocytes | Gpt/l | 12.2 ± 6.6 | 20.8 ± 12.4 | P < 0.01 |
Banded neutrophils | % | 73 ± 11 | 70 ± 10 | n.s. |
Segmented neutrophils | % | 18 ± 11 | 18 ± 12 | n.s. |
C-reactive protein | mg/l | 190 ± 130 | 165 ± 119 | P < 0.01 |
Procalcitonin | ng/l | 10.1 ± 23.4 | 6.8 ± 14.6 | P < 0.01 |
Endotoxin | pg/ml | 16.4 ± 7.7 | 13.5 ± 5.5 | P < 0.05 |
Temperature | °C | 36.86 ± 0.97 | 36.73 ± 0.87 | n.s. |
Hemodynamic | ||||
Noradrenaline | μg/kg/minute | 0.10 ± 0.12 | 0.08 ± 0.10 | P< 0.05 |
MAP | mmHg | 76.9 ± 12.8 | 80.2 ± 9.8 | n.s. |
Pulse | bpm | 101 ± 19 | 101 ± 20 | n.s. |
Respiration | ||||
PaO2 | kPa | 13.0 ± 3.1 | 13.4 ± 4.0 | n.s. |
FiO2 | % | 40.8 ± 19.4 | 40.0 ± 16.3 | n.s. |
Coagulation | ||||
INR | 1.29 ± 0.25 | 1.44 ± 0.29 | P < 0.01 | |
aPTT | sec | 53.8 ± 50.2 | 85.8 ± 47.4 | P < 0.05 |
Antithrombin III | % | 65.6 ± 16.8 | 58.4 ± 15.3 | P < 0.01 |
Fibrinogen | g/l | 5.07 ± 2.25 | 4.62 ± 2.15 | P < 0.01 |
D-Dimere | μg/l | 752 ± 505 | 853 ± 450 | P < 0.05 |
Platelets | Gpt/l | 163 ± 130 | 169 ± 152 | n.s. |
Other | ||||
Urea | mmol/l | 13.5 ± 7.5 | 15.0 ± 8.4 | P < 0.01 |
Creatinin | μmol/l | 129 ± 99 | 132 ± 108 | n.s. |
Bilirubin | μmol/l | 33.1 ± 44.2 | 35.4 ± 44.8 | n.s. |