From: Impact of de-escalation therapy on clinical outcomes for intensive care unit-acquired pneumonia
Variable | Adjusted hazard ratiob | 95% CI | P value |
---|---|---|---|
Inadequacy of antibiotics | 2.145 | 0.483 to 9.536 | 0.316 |
Non-de-escalation of antibiotics | 3.988 | 0.047 to 6.985 | 0.245 |
Baseline APACHE II score (reference score <19) | Â | Â | 0.198 |
   20 to 23 | 2.528 | 0.609 to 10.493 | 0.201 |
   ≥24 | 7.611 | 0.615 to 94.179 | 0.114 |
5-day APACHE II score (reference score <19) | Â | Â | 0.011 |
   20 to 23 | 4.934 | 0.974 to 25.003 | 0.054 |
   ≥24 | 12.839 | 2.359 to 69.883 | 0.003 |
5-day CPIS (reference score 4 to 6) | Â | Â | 0.017 |
   7 to 9 | 2.154 | 0.361 to 12.861 | 0.400 |
   ≥10 | 26.782 | 2.180 to 329.011 | 0.010 |