Skip to main content

Table 4 Cox regression analyses of factors associated with LOS in the ICU of the 86 included patients

From: Cytomegalovirus reactivation and associated outcome of critically ill patients with severe sepsis

 

Univariable analysis

Multivariable analysis

Factor

HR

P-v alue

HR

95% CI

P-v alue

CMV reactivation

3.101

0.009

3.365

1.233 to 9.183

0.018

SAPS II at inclusion

1.065

<0.001

1.045

1.008 to 1.083

0.016

Septic Shock present

2.282

0.081

1.486

0.535 to 4.127

0.447

ICU stay before enrolment

1.006

0.577

1.020

0.996 to 1.044

0.104

HSV detection in respiratory secretions

1.302

0.501

1.338

0.595 to 3.013

0.481

Optimized model

CMV reactivation

  

2.441

1.011 to 5.897

0.047

SAPS II at inclusion

  

1.055

1.020 to 1.091

0.002

Landmark analysis for Day 0, Day 7 and Day 14

Day 0 (86 patients, 12 of them with CMV reactivation)

   CMV reactivation

1.017

0.975

1.061

0.367 to 3.068

0.913

   SAPS II at inclusion

1.065

<0.001

1.065

1.030 to 1.101

<0.001

Day 7 (64 patients, 16 of them with CMV reactivation)

   CMV reactivation

2.274

0.112

2.853

1.003 to 8.117

0.049

   SAPS II at inclusion

1.071

0.001

1.074

1.033 to 1.116

<0.001

Day 14 (47 patients, 17 of them with CMV reactivation)

   CMV reactivation

2.109

0.164

2.538

0.861 to 7.479

0.091

   SAPS II at inclusion

1.065

0.010

1.069

1.021 to 1.120

0.004

  1. CI, confidence interval; CMV, cytomegalovirus; HR, hazard ratio; HSV, herpes simplex virus; LOS, length of stay; SAPS, Sequential Organ Failure Assessment score.