Cytomegalovirus reactivation and associated outcome of critically ill patients with severe sepsis

Table 1 Demography and underlying conditions of included patients (n = 86)

	All patients	Active CMV infection		P-value
		Yes	No
	n = 86 (100%)	n = 35 (40.69%)	n = 51 (59.31%)
Demographic data
Age (years)^a	68.0 (59 to 76)	68.0 (52 to 73)	69.0 (59 to 76)	0.237
Male sex (n (%))	67 (77.9)	27 (77.1)	40 (78.4)	0.888
Surgical interventions requiring intensive care (n)
Neurosurgery	4	2	2
Abdominal surgery	33	14	19
Cardiovascular surgery	18	7	11
Other surgical procedures	9	6	3
All surgical interventions	64	29	35
Medical diseases requiring intensive care (n)
Liver disease	1	1	0
Coronary heart disease	2	0	2
Infections in the internal ICU	16	4	12
Other	3	1	2
All medical diseases	22	6	16	0.137
Infection causing severe sepsis (n (%)) ^b
Pneumonia	22 (25.9%)	11 (31.4%)	11 (22.0%)	0.329
Peritonitis	34 (40.5%)	12 (35.3%)	22 (44.0%)	0.425
Urinary tract infection	7 (8.5%)	4 (12.5%)	3 (6.0%)	0.263*
Catheter-associated bacteremia	6 (7.3%)	3 (9.4%)	3 (6.0%)	0.435*
Other	38 (55.1%)	18 (66.7%)	20 (47.6%)	0.121
Severity of illness at enrolment
Duration of ICU stay (days) ^c,d	4.0 (2 to 9)	5.0 (2 to 11)	4.0 (2 to 9)	0.245
SAPS II Score^a	43.0 (36 to 51)	43.0 (33 to 47)	44.0 (37 to 33)	0.150
SOFA Score^a	8.0 (7 to 11)	8.0 (6 to 10)	9.0 (7 to 12)	0.060
Septic Shock present (n (%))	55 (65.5%)	19 (57.6%)	36 (70.6%)	0.221
Transfusion of packed red cells^a,d	2.0 (0 to 6)	2.0 (0 to 5)	3.0 (0 to 8.5)	0.561
Duration of ventilation (days) ^c,d	4.0 (2 to 9)	5.0 (2 to 11)	3.0 (2 to 9)	0.157
Surgical interventions ^a,d	1.0 (1 to 2)	1.0 (1 to 2)	1.0 (1 to 2)	0.586
Horowitz index (paO₂/fiO₂) <200 (n (%))	56 (65.9)	23 (67.7)	33 (64.7)	0.779

^aMedian (interquartile range), ^bAll infections sum up to more than 100%, because more than one infection could be noted in one patient, ^cMedian (interquartile range), ^dDuring the actual hospital stay until enrolment into the study * Fisher's exact test.
CMV, cytomegalovirus; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment score.

ISSN: 1364-8535