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Table 1 Demography and underlying conditions of included patients (n = 86)

From: Cytomegalovirus reactivation and associated outcome of critically ill patients with severe sepsis

  All patients Active CMV infection P-value
   Yes No  
  n = 86 (100%) n = 35 (40.69%) n = 51 (59.31%)  
Demographic data     
   Age (years)a 68.0 (59 to 76) 68.0 (52 to 73) 69.0 (59 to 76) 0.237
   Male sex (n (%)) 67 (77.9) 27 (77.1) 40 (78.4) 0.888
Surgical interventions requiring intensive care (n)     
   Neurosurgery 4 2 2  
   Abdominal surgery 33 14 19  
   Cardiovascular surgery 18 7 11  
   Other surgical procedures 9 6 3  
   All surgical interventions 64 29 35  
Medical diseases requiring intensive care (n)     
   Liver disease 1 1 0  
   Coronary heart disease 2 0 2  
   Infections in the internal ICU 16 4 12  
   Other 3 1 2  
   All medical diseases 22 6 16 0.137
Infection causing severe sepsis (n (%)) b     
   Pneumonia 22 (25.9%) 11 (31.4%) 11 (22.0%) 0.329
   Peritonitis 34 (40.5%) 12 (35.3%) 22 (44.0%) 0.425
   Urinary tract infection 7 (8.5%) 4 (12.5%) 3 (6.0%) 0.263*
   Catheter-associated bacteremia 6 (7.3%) 3 (9.4%) 3 (6.0%) 0.435*
   Other 38 (55.1%) 18 (66.7%) 20 (47.6%) 0.121
Severity of illness at enrolment     
   Duration of ICU stay (days) c,d 4.0 (2 to 9) 5.0 (2 to 11) 4.0 (2 to 9) 0.245
   SAPS II Scorea 43.0 (36 to 51) 43.0 (33 to 47) 44.0 (37 to 33) 0.150
   SOFA Scorea 8.0 (7 to 11) 8.0 (6 to 10) 9.0 (7 to 12) 0.060
   Septic Shock present (n (%)) 55 (65.5%) 19 (57.6%) 36 (70.6%) 0.221
   Transfusion of packed red cellsa,d 2.0 (0 to 6) 2.0 (0 to 5) 3.0 (0 to 8.5) 0.561
   Duration of ventilation (days) c,d 4.0 (2 to 9) 5.0 (2 to 11) 3.0 (2 to 9) 0.157
   Surgical interventions a,d 1.0 (1 to 2) 1.0 (1 to 2) 1.0 (1 to 2) 0.586
   Horowitz index (paO2/fiO2) <200 (n (%)) 56 (65.9) 23 (67.7) 33 (64.7) 0.779
  1. aMedian (interquartile range), bAll infections sum up to more than 100%, because more than one infection could be noted in one patient, cMedian (interquartile range), dDuring the actual hospital stay until enrolment into the study * Fisher's exact test.
  2. CMV, cytomegalovirus; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment score.