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Table 3 Areas under the receiver operating characteristic curve (95% confidence intervals) for prediction of fluid responsiveness (increase in cardiac index ≥10% (A) or ≥15% (B)) by baseline values, according to global ejection fraction

From: Cardiac filling volumes versus pressures for predicting fluid responsiveness after cardiovascular surgery: the role of systolic cardiac function

 

GEF <20% (n= 12)

GEF ≥20% (n= 20)

 

AUC

P -value

Cutoff

AUC

P -value

Cutoff

A

      

GEDVI

0.56 (0.39 to 0.73)

0.511

902

0.72 (0.58 to 0.83)

0.002

890

CVP

0.76 (0.59 to 0.88)

0.001

6

0.73 (0.60 to 0.84)

<0.001

2

PAOP

0.79 (0.57 to 0.93)

0.004

10

0.65 (0.46 to 0.81)

0.129

9

B

      

GEDVI

0.62 (0.44 to 0.77)

0.33

1279

0.89 (0.78 to 0.95)

<0.001

623

CVP

0.77 (0.60 to 0.89)

0.002

5

0.73 (0.60 to 0.84)

0.013

4

PAOP

0.84 (0.63 to 0.96)

<0.001

9

0.50 (0.32 to 0.69)*

0.98*

9

  1. CVP, central venous pressure, mm Hg; GEDVI, global end diastolic volume index, mL/m2; GEF, global ejection fraction; PAOP, pulmonary artery occlusion pressure, mm Hg.
  2. *P = 0.008 vs. AUC GEDVI; for A and low GEF: PAOP sensitivity 92%, specificity 60%, positive predictive value 75%, negative predictive value 86%; for normal GEF: GEDVI sensitivity 82%, specificity 56%, positive predictive value 42%, negative predictive value 89%; for B and low GEF: PAOP sensitivity 86%, specificity 69%, positive predictive value 55%, negative predictive value 92%; for normal GEF: GEDVI sensitivity 71%, specificity 94%, positive predictive value 63%, negative predictive value 93%.
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Critical Care

ISSN: 1364-8535