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Table 4 Baseline characteristics and outcomes in intervention and control groups in 14 studies included in meta-analysis

From: A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis

Author:

Year

Creatinine*

Urea*

APACHE II score

Dialysis-Free (%)

Duration of RRT (days)

ICU Length of Stay (days)

Mortality at 28-days (%)

  

Early

Late

Early

Late

Early

Late

Early

Late

Early

Late

Early

Late

Early

Late

Bouman [10]

2002

5 (4)**

6 (4)**

NR

NR

21.7(5.5)

23.6(8.3)

17

22

5.7

6.6

NR

NR

11/35

9/36

Sugahara [32]

2004

256

265

NR

NR

19(2)

18(3)

10

2

NR

NR

NR

NR

2/14

12/14

Liu [21]

2006

301

415

16.9

41.0

NR

NR

NR

NR

NR

NR

NR

NR

43/122

50/121

Sabater [33]

2008

NR

NR

NR

NR

24(8)

29(9)

NR

NR

6

7

NR

NR

1/9

16/23

Bagshaw [34]

2009

230

396

15.0 (5.4)

38.8 (12)

11.1 (3)§

10.7 (3)§

91

74

4 (2-13)

6 (2-15)

13 (7-24)

13 (6-28)

392/618

380/619

Bagshaw [35]

2010

273

489

13.5

38.0

31(9.3)

28.1(6.7)

22

30

NR

NR

12

14

67/117

54/117

Gettings [15]

1999

148

238

15.2 (4.6)

33.7 (10)

NR

NR

16

11

17.7

20.2

NR

NR

25/41

47/59

Elahi [38]

2004

328

379

23.9 (12)

26.8 (22)

NR

NR

NR

NR

4.61

4.57

8.5

12.5

8/28

12/36

Dermirkilic [13]

2004

NR

NR

NR

NR

NR

NR

NR

NR

4.32

4.56

7.8

12.4

8/27

15/34

Andrade [36]

2007

583

548

73.9 (6.6)

82.8 (6.9)

24.5 (1.4)

26 (1.2)

NR

NR

NR

NR

20

13.6

3/18

10/15

Wu [42]

2007

256

415

16.5 (7)

42.4 (12)

18.2 (5.1)

20.5 (5.3)

NR

NR

NR

NR

NR

NR

34/54

22/26

Manche [40]

2008

233

404

14.4 (3.1)

35.2 (18)

NR

.

NR

NR

1.8

6.5

NR

NR

14/56

13/15

Iyem [39]

2009

186

256

19.5 (2.7)

24.3 (1.9)

NR

.

95

87

1.6

4.1

2

4

5/95

6/90

Shiao [41]

2009

292

336

24.6 (14)

29.2 (14)

18.2 (5.4)

18.8 (6.3)

21

10

NR

NR

NR

NR

22/51

35/47

Carl [37]

2010

442

514

23.6 (7.2)

48.9 (10)

24.8 (6.2)

24.7 (6.1)

NR

NR

NR

NR

27

39.1

44/85

42/62

  1. * Continuous variables reported as means and standard deviations when given.
  2. ** Bouman et al. reported creatinine clearance (ml/minute).