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Table 4 Baseline characteristics and outcomes in intervention and control groups in 14 studies included in meta-analysis

From: A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis

Author: Year Creatinine* Urea* APACHE II score Dialysis-Free (%) Duration of RRT (days) ICU Length of Stay (days) Mortality at 28-days (%)
   Early Late Early Late Early Late Early Late Early Late Early Late Early Late
Bouman [10] 2002 5 (4)** 6 (4)** NR NR 21.7(5.5) 23.6(8.3) 17 22 5.7 6.6 NR NR 11/35 9/36
Sugahara [32] 2004 256 265 NR NR 19(2) 18(3) 10 2 NR NR NR NR 2/14 12/14
Liu [21] 2006 301 415 16.9 41.0 NR NR NR NR NR NR NR NR 43/122 50/121
Sabater [33] 2008 NR NR NR NR 24(8) 29(9) NR NR 6 7 NR NR 1/9 16/23
Bagshaw [34] 2009 230 396 15.0 (5.4) 38.8 (12) 11.1 (3)§ 10.7 (3)§ 91 74 4 (2-13) 6 (2-15) 13 (7-24) 13 (6-28) 392/618 380/619
Bagshaw [35] 2010 273 489 13.5 38.0 31(9.3) 28.1(6.7) 22 30 NR NR 12 14 67/117 54/117
Gettings [15] 1999 148 238 15.2 (4.6) 33.7 (10) NR NR 16 11 17.7 20.2 NR NR 25/41 47/59
Elahi [38] 2004 328 379 23.9 (12) 26.8 (22) NR NR NR NR 4.61 4.57 8.5 12.5 8/28 12/36
Dermirkilic [13] 2004 NR NR NR NR NR NR NR NR 4.32 4.56 7.8 12.4 8/27 15/34
Andrade [36] 2007 583 548 73.9 (6.6) 82.8 (6.9) 24.5 (1.4) 26 (1.2) NR NR NR NR 20 13.6 3/18 10/15
Wu [42] 2007 256 415 16.5 (7) 42.4 (12) 18.2 (5.1) 20.5 (5.3) NR NR NR NR NR NR 34/54 22/26
Manche [40] 2008 233 404 14.4 (3.1) 35.2 (18) NR . NR NR 1.8 6.5 NR NR 14/56 13/15
Iyem [39] 2009 186 256 19.5 (2.7) 24.3 (1.9) NR . 95 87 1.6 4.1 2 4 5/95 6/90
Shiao [41] 2009 292 336 24.6 (14) 29.2 (14) 18.2 (5.4) 18.8 (6.3) 21 10 NR NR NR NR 22/51 35/47
Carl [37] 2010 442 514 23.6 (7.2) 48.9 (10) 24.8 (6.2) 24.7 (6.1) NR NR NR NR 27 39.1 44/85 42/62
  1. * Continuous variables reported as means and standard deviations when given.
  2. ** Bouman et al. reported creatinine clearance (ml/minute).