Computed tomographic assessment of lung weights in trauma patients with early posttraumatic lung dysfunction

Table 3 Patient subgroups defined by different ranges of lung weights^a

Patient subgroups	Atelectasis (≤ reference range)	Above reference range	Consolidation
Definition	M_lung ≤1,164 g	M_lung >1,164 g	M_lung >1,380 g
Number of patients^b	46 (59%)	32 (41%)	17 (22%)
Median age^c, yr	45 (32 to 53)	28 (17 to 46)	21 (17 to 48)
Median PaO₂/FiO₂^ns, mmHg	184 (128 to 252)	136 (78 to 238)	132 (68 to 230)
Median Lung Injury Score^e	2.3 (1.6 to 2.6)	2.7 (2.3 to 3.3)	3.0 (2.3 to 3.3)
Median Injury Severity Score^ns	34 (29 to 45)	41 (28 to 50)	36 (25 to 50)
Median AIS-T score^b	4 (4 to 4)	4 (4 to 4)	4 (4 to 4)
Median Thoracic Trauma Severity Score^ns	11 (8 to 14)	12 (9 to 15)	12 (11 to 15)
Median Glasgow Coma Scale score^e	14 (10 to 15)	6 (3 to 12)	7 (3 to 15)
Median volume of intravenous fluids ^ns, ml	2,000 (1,000 to 3,000)	2,000 (1,500 to 2,875)	2,500 (1,500 to 3,000)
Median time to CT^ns, min	135 (90 to 220)	112 (90 to 177)	131 (103 to 227)
Median ventilator-free days^d	19 (10 to 25)	15 (0 to 19)	15 (0 to 19)
Median ICU-free days^c	14 (2 to 22)	1 (0 to 13)	5 (0 to 14)
Median V_lung^e, ml	2,832 (2,226 to 3,669)	3,812 (3,134 to 4,696)	3,696 (3,019 to 4,668)
Median M_lung^b, g	899 (787 to 1,048)	1,398 (1,265 to 1,972)	1,930 (1,461 to 2,065)
Median M_non^e, %	16 (10 to 25)	34 (18 to 52)	40 (33 to 57)

^aAll values are given as medians with interquartile ranges. Atelectasis, patients with lung weights (M_lung) within the reference interval (that is, 584 to 1,164 g) for normal M_lung; above reference, patients with M_lung values exceeding the upper limit of the reference interval (that is, 1,164 g); consolidation, patients with M_lung values exceeding the lower limit of the 95% confidence interval of the mean M_lung values reported for patients with acute lung injury (that is, 1,380 g [10]); PaO₂/FiO₂, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen; AIS-T, Abbreviated Injury Scale of the Thorax; time to CT, interval between trauma and computed tomography (CT); ventilator-free days, number of days without mechanical ventilation within a period of 28 days; ICU, intensive care unit; ICU-free days, number of days without ICU treatment within a period of 28 days; V_lung, total lung volume; M_lung, total lung mass; M_non, percentage mass of nonaerated lung compartment (percentage of M_lung value); ^ns, not significant. ^bNo statistical test performed. ^cP < 0.05, ^dP < 0.001 and ^eP < 0.01, respectively, for the Kruskal-Wallis test over all groups.

ISSN: 1364-8535