Computed tomographic assessment of lung weights in trauma patients with early posttraumatic lung dysfunction

Table 1 Demographic data^a

Patient demographics	ALI	Reference ventilated	Reference spontaneous
Number of patients	78	43	31
Median age^ns	42 (23 to 51)	27 (21 to 45)	32 (22 to 44)
Sex (male/female)^b	61/17	37/6	19/12
Median height^b, cm	176 (173 to 180)	175 (170 to 183)	174 (168 to 183)
Median weight^b, kg	80 (74 to 90)	75 (70 to 82)	73 (59 to 85)
Median Body Mass Index^b, kg m^-2	26 (23 to 28)	24 (23 to 26)	23 (21 to 24)
Median PaO₂/FiO₂, mmHg	169 (95 to 240)	560 (506 to 616)^d	n.a.
Median Lung Injury Score	2.3 (2.0 to 3.0)	n.a.	n.a.
Median Injury Severity Score^c	36 (29 to 48)	20 (12 to 26)^d	12 (6 to 16)^d,e
Median AIS-T	4 (4 to 4)	n.a.	n.a.
Median Thoracic Trauma Severity Score^b	11 (9 to 14)	n.a.	n.a.
Median Glasgow Coma Scale score^c	11 (4 to 15)	11 (7 to 15)	15 (15 to 15)^d,e
Median volume of intravenous fluids ^c, ml	2,000 (1,125 to 3,000)	1,000 (500 to 1,500)^d	1,000 (500 to 1,000)^d
Median time to CT^ns, min	122 (90 to 207)	105 (79 to 129)	100 (81 to 136)
Median ventilator-free days^b	17 (4 to 23)	27 (19 to 27)	n.a.
Median ICU-free days^b	7 (0 to 17)	22 (10 to 26)	n.a.

^aAll values are given as medians with interquartile ranges. ALI, patients with acute lung injury at admission; reference ventilated, mechanically ventilated patients with normal lungs; reference spontaneous, spontaneously breathing patients with normal lungs; Body Mass Index, weight in kilograms divided by the square of the height in meters; PaO₂/FiO₂, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen; AIS-T, Abbreviated Injury Scale of the Thorax; time to CT, interval between trauma and computed tomography (CT); ventilator-free days, number of days without mechanical ventilation within a period of 28 days; ICU, intensive care unit; ICU-free days, number of days without ICU treatment within a period of 28 days; n.a., not applicable; ^ns, not significant. Positive end-expiratory pressure (PEEP) was 10 cmH₂O in all mechanically ventilated patients except for five; in three patients, PEEP >10 cmH₂O was already applied before admission and two patients were spontaneously breathing during CT. ^bNo statistical test performed. ^cP < 0.001 for the Kruskal-Wallis test over all groups. ^dP < 0.001 versus ALI. ^eP < 0.05 versus reference ventilated group.

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