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Table 1 Basic characteristics and physiological data of patients according to their study groupsa

From: Balanced massive transfusion ratios in multiple injury patients with traumatic brain injury

 

AIS score, head <3

AIS score, head ≥3

Patient characteristics

FFP:pRBC ratio ≤1:2

FFP:pRBC ratio >1:2

P value

FFP:pRBC ratio ≤1:2

FFP:pRBC ratio >1:2

P value

Number of patients (%)

212 (17%)

426 (34.1%)

 

167 (13.4%)

445 (35.6%)

 

Mean age, yr (±SD)

45.9 ± 20

42.0 ± 17.2

0.049

40.5 ± 19.2

40.2 ± 18.2

0.947

Males, n (%)

149 (70.3%)

330 (77.5%)

0.048

111 (66.5%)

314 (70.6%)

0.327

Blunt trauma mechanism, n (%)

191 (90.1%)

379 (89%)

0.722

158 (94.6%)

417 (93.7%)

0.676

Mean ISS, points (±SD)

36.7 ± 15.3

35.4 ± 13.5

0.532

49.5 ± 14.9

47.2 ± 14.1

0.143

Mean GCS at trauma scene, points

10

12

0.001

7

7

0.571

Mean HR at trauma scene, beats/min (±SD)

105 ± 31

106 ± 25

0.907

106 ± 33

105 ± 28

0.240

Mean HR at hospital admission, beats/min (±SD)

105 ± 27

102 ± 26

0.222

103 ± 31

104 ± 26

0.686

Mean systolic BP at trauma scene, mmHg (±SD)

91 ± 34

95 ± 31

0.245

90 ± 35

93 ± 35

0.792

Mean systolic BP at hospital admission, mmHg (±SD)

93 ± 36

95 ± 30

0.411

92 ± 34

96 ± 30

0.313

Mean Hb, g/dl (±SD)

8.0 ± 2.7

8.4 ± 2.8

0.09

8.0 ± 2.9

8.4 ± 3.0

0.13

Mean BE, mM/l (±SD)

-8.9 ± 6.8

-7.0 ± 5.9

0.08

-9.3 ± 6.5

-7.3 ± 6.4

0.01

Mean PTT, seconds (±SD)

51.9 (±32.8)

50.9 (±31.1)

0.63

72.3(±49.3)

60.7(±37.5)

0.06

Mean quick, % (±SD)

54 (±23.7)

56 (±23.4)

0.33

54 (±24.2)

53 (±23.0)

0.69

Mean platelets, nl (±SD)

158 (±77.7)

165 (±75.6)

0.30

152 (±74.0)

160 (±71.6)

0.23

Coagulopathy, n (%)

152 (87.4%)

298 (82.3%)

0.14

118 (90.1%)

344 (88.4%)

0.61

  1. aAIS, Abbreviated Injury Scale; FFP, fresh frozen plasma; pRBC, packed red blood cell; SD, standard deviation; ISS, Injury Severity Score; GCS, Glasgow Coma Scale; HR, heart rate; BP, blood pressure; Hb, hemoglobin; BE, base excess; PTT, partial thromboplastin time. Coagulopathy was defined by the presence of at least one of the following conditions: PTT <38 seconds, Quick <70% and platelets <100,000/μl. In the TR-DGU the prothrombin time (PT) is documented as Quick's value where a value of <70% is equivalent to an INR (International Normalized Ratio) > 1.3.