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Table 4 Comparison of demographic and clinical characteristics among with pandemic 2009 influenza A (H1N1) virus infectiona

From: Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection

Variables

Survivors (n = 527)

Nonsurvivors (n = 134)

P value

Mean age, yr (±SD)

43.2 (13.9)

46.09 (15.2)

0.1

Male sex, n (%)

290 (54.0%)

74 (59.7%)

0.2

Mean APACHE II score (±SD)

12.5 (5.9)

18.8 (7.9)

<0.001

Mean SOFA score (±SD)

4.8 (2.8)

8.1 (4.3)

<0.001

Comorbidities, n (%)

   

   Pregnancy

33 (6.1%)

6 (4.8%)

0.6

   COPD

94 (17.5%)

15 (12.1%)

0.1

   Asthma

76 (14.2%)

11 (8.9%)

0.1

   Heart failure

28 (5.2%)

11 (8.9%)

0.1

   Obesity

194 (36.1%)

54 (43.5%)

0.1

   Diabetes

56 (10.4%)

15 (12.1%)

0.6

   Immunosuppression

13 (2.4%)

7 (5.6%)

0.07

   Hematological disease

19 (3.5%)

15 (12.1%)

<0.001

   Neuromuscular disease

17 (3.2%)

6 (4.8%)

0.4

   HIV infection

11 (2.0%)

4 (3.2%)

0.4

   Invasive MV

290 (54.0%)

118 (95.2%)

<0.001

   Shock

208 (38.7%)

89 (71.8%)

<0.001

   MODS

299 (55.7%)

107 (86.3%)

<0.001

   Coinfection

76 (14.2%)

30 (24.2%)

<0.01

  1. aSurvivors versus nonsurvivors. APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, sequential organ failure assessment; COPD, chronic obstructive pulmonary disease; HIV, human immunodeficiency virus; MV, mechanical ventilation; MODS, Multiple Organ Dysfunction Score.