Table 3 Correlations with suPAR serum concentrations at admission day

From: Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients

	All patients		Sepsis		Non-sepsis
Parameters	r	P	r	P	r	P
*Markers of inflammation*
TNF-α	0.571	< 0.001	0.555	< 0.001	0.583	0.001
CRP	0.411	< 0.001	0.408	< 0.001	-	n.s.
Procalcitonin	0.468	< 0.001	0.437	< 0.001	0.418	0.003
*Markers of organ function*
Creatinine	0.352	< 0.001	0.273	< 0.001	0.430	< 0.001
Urea	0.400	< 0.001	0.326	<0.001	0.458	< 0.001
Cystatin C	0.638	< 0.001	0.557	< 0.001	0.724	< 0.001
Cystatin C GFR	-0.649	< 0.001	-0.583	< 0.001	-0.714	< 0.001
Bilirubin	0.243	< 0.001	0.194	0.012	0.413	< 0.001
yGT	0.354	< 0.001	0.350	< 0.001	0.367	0.002
AP	0.441	< 0.001	0.379	< 0.001	0.599	< 0.001
PCHE	-0.492	< 0.001	-0.449	< 0.001	-0.438	< 0.001
Albumin	-0.444	< 0.001	-0.387	< 0.001	-0.430	0.003
INR	0.300	< 0.001	0.214	0.006	0.416	< 0.001
ATIII	-0.416	< 0.001	-0.300	0.006	-0.507	0.002
IGF-1	-0.379	< 0.001	-0.247	0.029	-0.625	< 0.001
Base excess	-0.217	0.001	-0.291	< 0.001	-	n.s.
*ICU treatment measures*
FiO₂	0.230	0.043	-	n.s.	-	n.s.
PEEP	0.319	0.004	0.265	0.042	-	n.s.
Norephinephrine dose	0.131	0.050	0.202	0.011	-	n.s.
*Clinical scoring*
APACHE II	0.345	< 0.001	0.353	< 0.001	-	n.s.
SOFA	0.337	0.004	-	n.s.	-	n.s.
SAPS2	0.271	0.004	0.346	0.002	-	n.s.

AP, alkaline phosphatase; APACHE, Acute Physiology and Chronic Health Evaluation; ATIII, antithrombin III; CRP, C-reactive protein; FiO₂, fraction of inspired oxygen; GFR, glomerular filtration rate; IGF-1, insulin-like growth factor 1; INR, international normalized ratio; PCHE, pseudocholinesterase; PEEP, Positive end-expiratory pressure; r, correlation coefficient; P, P-value; r and p-values by Spearman rank correlation; SAPS, simplified acute physiology score; SOFA, sequential organ failure assessment; TNF-α, tumor necrosis factor α; yGT, gamma-glutamyl-transferase.

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