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Table 1 Baseline patient characteristics and suPAR serum concentrations

From: Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients

Parameter

All patients

Sepsis

Non-sepsis

Number

273

197

76

Sex (male/female)

172/101

128/69

44/32

Age median (range) (years)

64 (18 to 90)

65 (20 to 90)

60 (18 to 85)

APACHE-II score median (range)

17 (0 to 40)

18 (0 to 40)

15 (0 to 31)

SOFA score median (range)

11 (0 to 17)

11 (2 to 17)

7 (0 to 16)

SAPS2 score median (range)

44 (0 to 80)

44.5 (0 to 79)

41.5 (13 to 80)

ICU days median (range)

9 (0 to 137)

12 ** (0 to 137)

6 ** (1 to 45)

Hospital days median (range)

27 (2 to 151)

30 ** (2 to 151)

14 ** (2 to 85)

Death during ICU n (%)

75 (32.8%)

60 (35.9%)

15 (24.2%)

Death during follow-up n (%)

111 (51.9%)

83 (53.5%)

28 (47.5%)

Mechanical ventilation n (%)

194 (73.2%)

144 (75%)

50 (68.5%)

Ventilation time median (range) (h)

126 (0 to 2,966)

180 * (0 to 2,966)

48.5 * (0 to 986)

pre-existing diabetes n (%)

87 (32.7%)

59 (30.7%)

28 (37.8%)

BMI median (range) (m2/kg)

25.8 (14.0 to 66.7)

25.9 (14.0 to 66.7)

25.8 (15.9 to 53.3)

suPAR Day 1 median (range) (ng/mL)

9.80 (0 to 20)

11.05 ** (1.87 to 20)

7.62 ** (0 to 20)

suPAR Day 3 median (range) (ng/mL)

10.83 (2.33 to 20)

12.11 * (2.59 to 20)

8.47 * (2.33 to 20)

suPAR Day 7 median (range) (ng/mL)

11.90 (3.67 to 20)

12.27 (3.94 to 20)

9.73 (3.67 to 20)

  1. APACHE, Acute Physiology and Chronic Health Evaluation; SAPS, simplified acute physiology score; SOFA, sequential organ failure assessment.
  2. Significant differences between sepsis and non-sepsis patients are marked by *(P < 0.05) or **(P < 0.001).