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Figure 5 | Critical Care

Figure 5

From: Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients

Figure 5

Prediction of long-term mortality by sequential suPAR serum concentrations. (A) Serum suPAR concentrations were significantly associated with the overall survival of critically ill patients. Survivors had significantly lower serum suPAR levels on admittance to ICU (P = 0.005) and on Day 3 (P = 0.009). (B and C) Kaplan-Meier survival curves of ICU patients are displayed, showing that patients with suPAR levels of upper quartile (on admission > 15 ng/mL, on Day 3 > 15 ng/mL; black) had an increased short-term mortality at the ICU as compared to patients with suPAR serum concentrations of lower quartile (on admission < 6 ng/ml, on Day 3 < 7 ng/ml; grey) or middle 50% (dotted line). P-values are given in the figure. (D and E) Kaplan-Meier survival curves of ICU patients are displayed, showing that patients with high suPAR levels (on admission > 8 ng/mL, on Day 3 >13 ng/mL; grey) had an increased overall mortality in the long-term follow-up as compared to patients with low suPAR serum concentrations. P-values are given in the figure.

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Critical Care

ISSN: 1364-8535