Figure 4From: Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patientsPrediction of ICU mortality by sequential suPAR serum concentrations. (A) Patients that die during the course of ICU treatment had significantly higher serum suPAR levels on admittance to ICU (P = 0.005), on Day 3 (P = 0.001) and Day 7 (P = 0.014) than survivors. (B and C) Kaplan-Meier survival curves of ICU patients are displayed, showing that patients with suPAR levels of upper quartile (on admission >15 ng/mL, on Day 3 > 15 ng/mL; black) had an increased short-term mortality at the ICU as compared to patients with suPAR serum concentrations of lower quartile (on admission < 6 ng/ml, on Day 3 < 7 ng/ml; grey) or middle 50% (dotted line). P-values are given in the figure. (D and E) Kaplan-Meier survival curves of ICU patients are displayed, showing that patients with high suPAR levels (on admission > 8 ng/mL, on Day 3 > 13 ng/mL; grey) had an increased short-term mortality at the ICU as compared to patients with low suPAR serum concentrations. P-values are given in the figure.Back to article page