Table 4 Risk factors for P. aeruginosa acquisition in the ICU (n = 126)
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
Risk factor | OR (95% CI) | P | OR (95% CI) | P |
SAPS II | ||||
≥43 (vs. <43) | 2.54 (0.89 to 7.24) | 0.08 | * | |
Age | ||||
≥70 years (vs. <70) | 4.61 (1.67 to 12.72) | 0.14 | * | |
Nasogastric tube | ||||
Equal to or more than nine cumulated days since admission (vs. less than nine days) | 7.66 (2.88 to 20.36) | <0.0001 | 7.72 (2.32 to 25.70) | 0.001 |
Antibiotic treatment not active against P. aeruginosa | ||||
More than three days (vs. zero to two days) | 2 (0.76 to 5.27) | 0.16 | *** | |
Antibiotic treatment active against P. aeruginosa** | ||||
per cumulated day since admission | 1.02 (0.95 to 1.10) | 0.54 | **** | |
Previous patient-induced environmental pressure | ||||
Equal to or more than one colonized patient on the same ward on the previous day (vs. zero) | 4.91 (1.47 to 16.39) | 0.01 | *** | |
Equal to or more than one colonized patient on the ICU on the previous day (vs. zero) | 1.14 (0.27 to 4.90) | 0.86 | **** | |
Previous tap water-induced environmental pressure | ||||
Equal to or more than one colonized tap water on the same ward on the previous day (vs. zero) | 2.37 (0.96 to 5.89) | 0.06 | $ | |
Equal to or more than one colonized tap water on the ICU on the previous day (vs. zero) | 3.79 (1.26 to 11.44) | 0.02 | 1.99 (0.67 to 5.88) | 0.21 |
Equal to or more than one colonized tap water in shared rooms on the previous day (vs. zero) | 4.63 (1.37 to 15.65) | 0.01 | 3.07 (0.93 to 10.16) | 0.07 |
Interaction between previous patient-induced environmental pressure and inactive antibiotics: | 0.03$$ | |||
If equal to or more than three days of inactive antibiotics | 1 | |||
- no colonized patient on the same ward on the previous day | 10.26 (1.83 to 57.43) | 0.01 | ||
- equal to or more than one colonized patient on the same ward on the previous day | ||||
If zero to two days of inactive antibiotics | ||||
- no colonized patient on the same ward on the previous day | 1 | |||
- equal to or more than one colonized patient on the same ward on the previous day | 1.00 (0.26 to 3.87) | 0.99 | ||