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Table 2 Variables by RAI, mortality, and neurologic outcome (N = 117, median values)

From: Hormonal responses upon return of spontaneous circulation after cardiac arrest: a retrospective cohort study

 

RAI

1 wk mortality

1 mo mortality

CPC

 

Yes

No

P-value

Survived

Dead

P- value

Survived

Dead

P- value

Good

Poor

P- value

 

(n = 68)

(n = 49)

 

(n = 87)

(n = 30)

 

(n = 65)

(n = 52)

 

(n = 35)

(n = 82)

 

Gender, M, n (%)

49 (72.1)

35 (71.4)

0.940

62 (71.3)

22 (73.3)

0.828

49 (75.4)

35 (67.3)

0.335

31 (88.6)

53 (64.6)

0.008*

Age (yr)

52

53

0.772

52

54

0.422

49

56

0.174

47

56

0.010*

BLS time (minutes)

6

4

0.076

5

6

0.093

5

6

0.207

4

6

0.200

Arrest time (minutes)

40

27

0.004*

31

50

<0.001*

25

44

<0.001*

25

38

0.010*

Epinephrine (mg)

5

2

<0.001*

3

7

0.001*

3

5

0.004*

3

4

0.338

HTN, yes, n (%)

18 (26.5)

15 30.6)

0.507

22 (25.3)

11 (36.7)

0.194

18 (27.7)

15 (28.8)

0.804

9 (25.7)

24 (29.3)

0.668

DM, yes, n (%)

6 (8.8)

7 (14.3)

0.283

8 (9.2)

5 (16.7)

0.298

5 (7.7)

8 (15.4)

0.152

1 (2.9)

12 (14.6)

0.102

APACHE II

23

22

0.889

22

27

0.001*

22

26

<0.001*

31

26

<0.001*

SOFA

10

9

0.062

9

12

<0.001*

9

11

0.001*

9

10

0.029*

Lactate (mmol/L)

9.40

7.55

0.013*

8.50

9.40

0.244

8.40

9.35

0.190

8.30

8.90

0.393

Cortisol, basal (μg/dL)

27.33

16.70

<0.001*

25.05

24.10

0.762

22.74

25.57

0.204

20.45

25.95

0.030*

Cortisol, 30 minutes (μg/dL)

28.74

28.54

0.543

28.89

27.35

0.380

28.29

29.54

0.584

26.45

29.32

0.273

Cortisol, 60 minutes (μg/dL)

29.12

32.46

0.100

29.67

24.64

0.154

29.20

30.74

0.946

29.02

31.53

0.572

ACTH (μg/dL)

7.85

2.12

0.006*

2.60

11.79

0.005*

2.35

9.41

0.002*

2.31

7.85

0.014*

ADH (pg/mL)

24.97

17.11

0.031*

19.81

28.65

0.037*

18.16

28.27

0.004*

14.42

24.80

0.001*

  1. *P < 0.05
  2. ACTH, adrenocorticotropic hormone; ADH, antidiuretic hormone, vasopressin; APACHE, Acute Physiology and Chronic Health Evaluation; BLS, basic life support; CPC, cerebral performance category (good CPC: 1 to 2, poor CPC: 3 to 5); DM, diabetes mellitus; HTN, hypertension; RAI, relative adrenal insufficiency; SOFA, The Sequential Organ Failure Assessment.