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Table 2 Variables by RAI, mortality, and neurologic outcome (N = 117, median values)

From: Hormonal responses upon return of spontaneous circulation after cardiac arrest: a retrospective cohort study

  RAI 1 wk mortality 1 mo mortality CPC
  Yes No P-value Survived Dead P- value Survived Dead P- value Good Poor P- value
  (n = 68) (n = 49)   (n = 87) (n = 30)   (n = 65) (n = 52)   (n = 35) (n = 82)  
Gender, M, n (%) 49 (72.1) 35 (71.4) 0.940 62 (71.3) 22 (73.3) 0.828 49 (75.4) 35 (67.3) 0.335 31 (88.6) 53 (64.6) 0.008*
Age (yr) 52 53 0.772 52 54 0.422 49 56 0.174 47 56 0.010*
BLS time (minutes) 6 4 0.076 5 6 0.093 5 6 0.207 4 6 0.200
Arrest time (minutes) 40 27 0.004* 31 50 <0.001* 25 44 <0.001* 25 38 0.010*
Epinephrine (mg) 5 2 <0.001* 3 7 0.001* 3 5 0.004* 3 4 0.338
HTN, yes, n (%) 18 (26.5) 15 30.6) 0.507 22 (25.3) 11 (36.7) 0.194 18 (27.7) 15 (28.8) 0.804 9 (25.7) 24 (29.3) 0.668
DM, yes, n (%) 6 (8.8) 7 (14.3) 0.283 8 (9.2) 5 (16.7) 0.298 5 (7.7) 8 (15.4) 0.152 1 (2.9) 12 (14.6) 0.102
APACHE II 23 22 0.889 22 27 0.001* 22 26 <0.001* 31 26 <0.001*
SOFA 10 9 0.062 9 12 <0.001* 9 11 0.001* 9 10 0.029*
Lactate (mmol/L) 9.40 7.55 0.013* 8.50 9.40 0.244 8.40 9.35 0.190 8.30 8.90 0.393
Cortisol, basal (μg/dL) 27.33 16.70 <0.001* 25.05 24.10 0.762 22.74 25.57 0.204 20.45 25.95 0.030*
Cortisol, 30 minutes (μg/dL) 28.74 28.54 0.543 28.89 27.35 0.380 28.29 29.54 0.584 26.45 29.32 0.273
Cortisol, 60 minutes (μg/dL) 29.12 32.46 0.100 29.67 24.64 0.154 29.20 30.74 0.946 29.02 31.53 0.572
ACTH (μg/dL) 7.85 2.12 0.006* 2.60 11.79 0.005* 2.35 9.41 0.002* 2.31 7.85 0.014*
ADH (pg/mL) 24.97 17.11 0.031* 19.81 28.65 0.037* 18.16 28.27 0.004* 14.42 24.80 0.001*
  1. *P < 0.05
  2. ACTH, adrenocorticotropic hormone; ADH, antidiuretic hormone, vasopressin; APACHE, Acute Physiology and Chronic Health Evaluation; BLS, basic life support; CPC, cerebral performance category (good CPC: 1 to 2, poor CPC: 3 to 5); DM, diabetes mellitus; HTN, hypertension; RAI, relative adrenal insufficiency; SOFA, The Sequential Organ Failure Assessment.