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Table 2 Baseline patient characteristics and NT-proCNP serum concentrations

From: Prognostic value of circulating amino-terminal pro-C-type natriuretic peptide in critically ill patients

Parameter

All patients

Sepsis

Non-sepsis

Number

273

197

76

Sex (male/female)

172/101

128/69

44/32

Age median (range) (years)

64 (18-90)

65 (20-90)

60 (18-85)

APACHE-II score median (range)

17 (2-40)

18 (3-40)

15 (2-31)

SAPS2 score median (range)

44 (0-80)

44.5 (0-79)

41.5 (13-80)

ICU days median (range)

9 (0-137)

12 ** (0-137)

6 ** (1-45)

Hospital days median (range)

27 (2-151)

30 ** (2-151)

14 ** (2-85)

Death during ICU n (%)

76 (27.8%)

61 (31.0%)

15 (19.7%)

Death during follow up n (%)

132 (50.2%)

101 (53.2%)

31 (42.5%)

Mechanical ventilation n (%)

194 (73.2%)

144 (75%)

50 (68.5%)

Ventilation time median (range) (hours)

126 (0-2966)

180 * (0-2966)

48.5 (0-986)

Pre-existing diabetes n (%)

88 (33.1%)

60 (31.3%)

28 (37.8%)

BMI median (range) (m²/kg)

25.8 (14.0-66.7)

25.9 (14.0-66.7)

25.8 (15.9-53.3)

NT-proCNP day 1 median (range)(pmol/L)

4.07 (0-42)

5.6 (0-42) **

1.48 (0-42) **

NT-proCNP day 3 median (range)(pmol/L)

4.79 (0-42)

5.81 (0-42) *

0.90 (0-42) *

NT-proCNP day 7 median (range)(pmol/L)

3.91 (0-42)

4.59 (0-42)

2.37 (0-41.34)

  1. APACHE, Acute Physiology and Chronic Health Evaluation; BMI, body mass index; NT-proCNP, amino-terminal pro-C-type natriuretic peptide; SAPS, simplified acute physiology score.
  2. Long-term follow-up data on survival were only available in 263 of 273 patients.
  3. Significant differences between sepsis and non-sepsis patients are marked by *(P < 0.05) or **(P < 0.001).