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Figure 2 | Critical Care

Figure 2

From: Prognostic value of circulating amino-terminal pro-C-type natriuretic peptide in critically ill patients

Figure 2

Serum NT-proCNP concentrations in critically ill patients are elevated in sepsis. (a) In patients with sepsis amino-terminal pro-C-type natriuretic peptide (NT-proCNP) serum concentrations are significantly (P < 0.001, U-test) higher as compared with patients with non-septic etiology of critical illness. Box plot are displayed, where the bold line indicates the median per group, the box represents 50% of the values, and horizontal lines show minimum and maximum values of the calculated non-outlier values; asterisks and open circles indicate outlier values. (b) Receiver operating characteristic (ROC) curve analyses comparing the diagnostic power in predicting sepsis of NT-proCNP in critically ill patients in a medical ICU (black line, area under the curve (AUC) = 0.661) with classical markers of inflammation and bacterial infection: C-reactive protein (CRP; grey line, AUC = 0.852), procalcitonin (PCT; dotted black line, AUC = 0.783), and white blood cell count (leucocytes; dotted grey line, AUC = 0.560).

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