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Figure 8 | Critical Care

Figure 8

From: Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis

Figure 8

Histology of treated and untreated mice. (a) Normal histology of lung obtained from sham mice. (b) Representative cecal ligation and puncture (CLP)-induced lung damage. (c) Representative lung of CLP mice treated with flavocoxid (20 mg/kg, ip, administered 1 hour after surgery, repeated every 12 hours). (d) Normal histology of liver obtained from sham mice. (e) Representative CLP-induced liver damage. (f) Representative liver of CLP mice treated with flavocoxid (20 mg/kg, ip, administered 1 hour after surgery, repeated every 12 hours). Sham and CLP mice were killed 18 hours after surgery. Histopathology was performed on lung and liver. Original magnification, ×20.

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