High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients

Table 3 Hemodynamic values before and after fluid challenge in fluid responders and nonresponders^a

	Nonresponders (n= 31)			Responders (n= 34)
Parameters	Before	After	P value	Before	After	P value
Mean arterial pressure, mmHg	71 ± 8	76 ± 8	0.01	71 ± 9	77 ± 9	<0.01
Heart rate, beats/minute	105 ± 21	102 ± 21	0.12	103 ± 17	98 ± 18	0.04
Central venous pressure, mmHg	12 ± 4	14 ± 3	<0.01	9 ± 4	12 ± 4	0.01
Pulmonary artery occlusion pressure, mmHg	14 ± 3	17 ± 6	0.02	12 ± 3	14 ± 5	<0.01
Mixed venous oxygen saturation, %	67 ± 9	67 ± 9	0.97	67 ± 7	71 ± 6	<0.01
Cardiac index, L/minute/m²	3 ± 0.9	3.2 ± 0.6	0.23	2.9 ± 0.8	3.6 ± 0.9	<0.01

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