High mixed venous oxygen saturation levels do not exclude fluid responsiveness in critically ill septic patients

Table 2 Hemodynamic values in fluid responders and nonresponders before and after fluid challenge^a

	Before fluid challenge			After fluid challenge
Parameters	Nonresponders ( n = 31)	Responders ( n = 34)	P value	Nonresponders ( n = 31)	Responders ( n = 34)	P value
Mean arterial pressure, mmHg	71 ± 8	71 ± 9	0.79	76 ± 8	77 ± 9	0.58
Heart rate, beats/minute	105 ± 21	103 ± 17	0.71	102 ± 21	98 ± 18	0.71
Central venous pressure, mmHg	12 ± 4	9 ± 4	0.008	14 ± 3	12 ± 4	0.18
Pulmonary artery occlusion pressure, mmHg	14 ± 3	12 ± 3	0.003	17 ± 6	14 ± 5	0.18
Mixed venous oxygen saturation, %	67 ± 9	67 ± 7	0.80	67 ± 9	71 ± 6	0.08
Cardiac index, L/minute/m²	3 ± 0.9	2.9 ± 0.8	0.73	3.2 ± 0.6	3.6 ± 0.9	0.11

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