Open Access

Does head elevation decreases cerebral blood flow?

  • Naresh Ramakrishnan1
Critical Care20002:5200

https://doi.org/10.1186/ccf-2000-5200

Published: 31 May 2000

Keywords

Cerebral blood flow cerebral perfusion pressure head position intracranial pressure jugular bulb pressure

Comments

An interesting observational study that looks at changes in cerebrovascular hemodynamics with changes in head elevation. It is usual to nurse patients with raised intra cranial pressure (ICP) with head elevation up to 30o, to facilitate venous drainage and treat the elevated ICP. However, the results of this study show, this may be accompanied by significant and linear drop in cerebral blood flow (CBF) during head elevation from 0o to 45o and this may potentially worsen the secondary injury. In addition, there was an increase in ICP with head elevation beyond 30o. The technique of CBF measurement by thermodilution is interesting in its own right and further details can be found in the additional comments below.

Introduction

Head elevation as a treatment to lower ICP in patients with intracranial hypertension has been challenged, as with head elevation both ICP and cerebral perfusion pressure (CPP) have been shown to fall. Changes in CBF however have not been quantified. Hence the rationale of this study to clarify the changes in cerebrovascular hemodynamics with head elevation.

Methods

  • Prospective, observational study in 37 adult patients with coma due to severe intracranial lesions.

  • The effect of 0o, 15o, 30o and 45o head elevation on CBF, CPP, ICP and arteriovenous pressure gradient were studied. The angles were measured using a goniometer

  • All patients were mechanically ventilated, sedated and paralyzed. The mean Glasgow coma scale was 6 (range 3-11).

  • CBF was measured using the thermodilution method.

  • ICP was measured by catheter inserted into the frontal horn of the lateral ventricle

  • Jugular catheters were inserted ipsilaterally into the vein on the side of the unilateral hemispheric lesion or on the right side in case of bihemispheric lesions.

Results

With head elevation from 0o to 45o, CBF decreased from 46.3 ± 4.8 to 28.7 ± 2.3 mL/min/100g (P < 0.01); CPP remained stable up to 30o and decreased from 62 ± 3 to 57 ± 4 mmHg between 30o and 45o (P < 0.05) and ICP decreased from 25 ± 2 to 14 ± 1 mmHg between 0o to 30o (P < 0.01) and increased from 14 ± 1 to 16 ± 2 (P < 0.05) between 30o and 45o.On multiple logistic regression analysis using a mathematical model, and even correcting for a calculated CPP, the CBF decreased by 0.15 mL/min/100g /10 head end elevation suggesting despite anything there was truly an independent decrease in blood flow.

Additional information

Melot C et al: Estimation of cerebral bloodflow at the bedside by continuos jugular thermodilution. J Cereb Blood Flow Metab 1996, 16:1263-1270

Authors’ Affiliations

(1)
The Royal Melbourne Hospital

References

  1. Moraine J-J, Berre J and Melot C: Is cerebral perfusion pressure a major determinant of cerebral blood flow during head elevation in comatose patients with severe intracranial lesions?. J Neurosurg. 2000, 92: 606-614.PubMedView ArticleGoogle Scholar

Copyright

© Current Science Ltd 2000

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