Volume 15 Supplement 1
Early administration of hydrocortisone replacement after advent of septic shock is a major determinant of final outcome
© Katsenos et al. 2011
Published: 1 March 2011
The CORTICUS trial doubts the value of hydrocortisone replacement for final outcome of septic shock . We hypothesized that the time of starting hydrocortisone may impact on the final outcome.
Retrospective analysis was made of prospectively collected data for 41 patients with septic shock (ACCP/SCCM 1992 definition) in the past year in two ICUs. Hydrocortisone was infused as suggested . The time lapsing from start of vasopressors until start of hydrocortisone was determined by the patients' charts.
Despite the observational approach, early start of hydrocortisone replacement in septic shock is a critical factor for outcome.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.