Volume 13 Supplement 1
Validation of the APACHE IV scoring system in patients with severe sepsis and comparison with the APACHE II system
© Dahhan et al; licensee BioMed Central Ltd. 2009
Published: 13 March 2009
APACHE IV is a successful scoring system assessing severity of illness and prognosis of ICU patients . It has been evaluated and validated in our patients for mortality outcome . The objective of this study was to validate the APACHE IV benchmark for patients admitted with severe sepsis and septic shock to the ICU and to compare the performance of the APACHE IV system with APACHE II.
In a cohort study at a tertiary-care medical-surgical ICU with a total of 35 acute-care beds, we included all ICU patients with the diagnosis of severe sepsis and septic shock between 1 January 2007 and 29 February 2008 from a prospectively collected ICU database. Observed mortality rates were compared with predicted mortality rates for both the APACHE II and APACHE IV scoring systems, and standardized mortality ratios (SMR) were determined. The mortality percentages were predicted using the APACHE IV system and were compared with the observed data. The chi-square test is used to calculate statistical significance for categorical data.
The present study demonstrates that the APACHE IV system performs acceptably in our patients with severe sepsis and septic shock and can be utilized as a performance assessment tool in our population.
This article is published under license to BioMed Central Ltd.