Volume 1 Supplement 1

17th International Symposium on Intensive Care and Emergency Medicine

Open Access

Valuation of bacteriological quantitative cultures obtained by broncho-alveolar lavages in ventilator-associated pneumonia

  • D Gruson1,
  • G Hilbert1,
  • C Scheyder1,
  • G Gbikpi-Benissan1 and
  • JP Cardinaud1
Critical Care19971(Suppl 1):P041

DOI: 10.1186/cc47

Published: 1 March 1997

Aims of the study

Quantitative cultures obtained by protected specimen brush (PSB) with at least one microorganism > 103 cfu/ml were the reference for ventilator-associated pneumonia diagnosis. This prospective study compared the bacteriological results of broncho-alveolar lavages (BAL) to PSB.

Patients and methods

In 100 cases of late ventilator-associated pneumonia (13 ± 4 days of ventilation), we realized PSB then BAL. Seventy-five specimens were realized on antibiotherapy era and 25 without antibiotherapy treatment. We calculated the sensitivity (SEN), specificity (SPE), the positive and negative predictive value (PPV, NPV), and the efficiency (EFF).

Results

See table.

Conclusion

Quantitative cultures obtained by BAL was an alternative for ventilator-associated nosocomial pneumonia, particularly if the antibiotherapy was stopped before BAL performed.

Table 1

n

BAL+PSB+

BAL+PSB-

BAL-PSB+

BAL-PSB-

Total = 100

29

29

3

39

   With ATB

18

25

3

29

   Without ATB

11

4

0

10

Table 2

n

SEN %

SPE %

PPV %

NPV %

EFF %

Total =100

90.6

57.3

50

92.8

68

   With ATB

85.7

53.7

41.9

90.6

62.7

   Without ATB

100

71.4

73.3

100

84

Authors’ Affiliations

(1)
Réanimation Médicale B, Hôpital Pellegrin

Copyright

© Current Science Ltd 1997

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