Volume 16 Supplement 3
Monocytic and neutrophilic CD11b and CD64 in severe sepsis
© Jämsä et al.; licensee BioMed Central Ltd. 2012
Published: 14 November 2012
Monocytic and neutrophilic CD11b and CD64 expressions were analyzed from 27 patients with severe sepsis, seven OPCABG patients and from eight ICU patients who did not fulfill any SIRS criteria. Blood samples were collected within 48 hours from the beginning of severe sepsis or in non-SIRS patients from ICU admission and two consecutive days (D0, D1, D2). From surgical patients, the first samples were taken on the day of surgery before the skin incision and two consecutive days (D0, D1, D2). In addition 10 healthy individuals served as controls. Samples were collected, processed and analyzed using flow cytometry as previously described .
Based on this study, monocytic CD11b and neutrophilic CD64 could be helpful in distinguishing severe sepsis from nonseptic inflammation and healthy controls.
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